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Model 2304

Only from AVIA Biosystems


The first fully automated
Isothermal Chemical Denaturation (ICD) systems


New Protein Stability Analysis Systems Accelerate Biologics Development

The new Isothermal Chemical Denaturation (ICD) Systems from AVIA will help you accelerate your biologics development programs.

·         Until now stability has been measured by heating proteins until they denature.  But, what does Tm really tell you about the stability of your product at room or lower temperature?  Practically nothing.

·         Only ICD measures how much protein is in the correct native conformation and how much is denatured and prone to aggregate at room temperature or experimental temperature.

·         Better yet, ICD requires only 25-50 µg of protein to test a formulation or processing condition.  With so little protein required, you are able to test more conditions earlier leading to better decisions and lower risk of following misleading or highly limited data.

The result: you obtain more and better stability information sooner and at lower cost.

No other company offers the breadth and depth of ICD expertise and products.

To learn more about how ICD technology can help you, please contact us for a free consultation or to schedule a webinar or on-site seminar for you and your colleagues.

For more information contact:



Visit us at PEGS 2014
Boston Seaport World Trade Center May 5-9
Conference booth #133

Attend the Luncheon seminar on Tuesday May 6th 12:45

"Automated Chemical Denaturation as a Tool to Evaluate Protein Stability and Optimize the Formulation of Biologics”

Ernesto Freire, PhD, Professor of Biology and Biophysics, Johns Hopkins University



ICD systems are available for:

·         Protein construct stability evaluations

·         Process conditions optimization

·         Pre-formulations screening

·         Formulations optimization

·         Ligand Binding Studies


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